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. 2015 Feb 6;10(2):e0116947. doi: 10.1371/journal.pone.0116947

Table 5. Gut organ growth and stomach pH of 17 d-old rats after gavage feeding a microbial-derived protease in increasing doses, or water (control) during 14–16 days of age.

Stomach Stomach SI Proximal SI Distal SI Cecum Pancreas Liver
weight pH length weight weight weight weight weight
Groups mg/g b.wt cm/g b.wt mg/g b.wt mg/g b.wt mg/g b.wt mg/g b.wt mg/g bwt
Control 6.2 ± 0.2 4.4 ± 0.6 1.4 ± 0.1 15.7 ± 1.6 13.2 ± 1.8 2.3 ± 0.2 3.2 ± 0.2 32.5 ± 2.5
Protease, mg/g b.wt:
0.0625 6.1 ± 0.3 4.1 ± 0.2 1.5 ± 0.0 16.4 ± 0.8 13.3 ± 1.4 2.3 ± 0.2 3.0 ± 0.4 31.7 ± 1.1
0.125 6.4 ± 0.3 4.1 ± 0.4 1.5 ± 0.1 17.6 ± 1.5 14.7 ± 1.1 2.6 ± 0.31 3.2 ± 0.3 32.8 ± 1.7
0.25 6.3 ± 0.4 3.4 ± 0.7 1.6 ± 0.1** 19.3 ± 2.0** 15.4 ± 1.7* 3.0 ± 0.2*** 3.4 ± 0.4 33.0 ± 1.6
0.5 6.9 ± 0.7 3.4 ± 0.6* 1.8 ± 0.1*** 28.2 ± 1.7*** 18.6 ± 1.0*** 4.2 ± 0.1*** 5.0 ± 0.2*** 38.5 ± 2.4

The organ results (mean ± SD, n = 5–6) are presented per gram body weight (g b.wt). Significant differences between protease-fed and control groups are indicated by

* P < 0.05,

**P < 0.01,

*** P < 0.001; SI = small intestine.