Table 2. Baseline characteristics of patients receiving short-course (< 56 day) or long-course (≥ 56 days) antibiotics for M. ulcerans infection.
| Short-course (n = 62) | Long-course (n = 145) | p value | |
|---|---|---|---|
| Sex | |||
| Male | 25 (40%) | 85 (59%) | p = 0.02 |
| Female | 37 (60%) | 60 (41%) | |
| Age | |||
| < 60 years | 24 (39%) | 80 (55%) | p = 0.03 |
| ≥ 60 years | 38 (61%) | 65 (45%) | |
| Immune suppression | |||
| No | 54 (87%) | 137 (94%) | p = 0.07 |
| Yes | 8 (13%) | 8 (6%) | |
| Diabetes | |||
| No | 54 (87%) | 133 (92%) | p = 0.30 |
| Yes | 8 (13%) | 12 (8%) | |
| Type of lesion | |||
| Ulcerative | 56 (90%) | 121 (83%) | p = 0.07 |
| Nodular | 5 (8%) | 6 (4%) | |
| Plaque | 0 (0%) | 2 (1%) | |
| Oedematous | 1 (2%) | 16 (11%) | |
| WHO category | |||
| 1 | 57 (92%) | 113 (77%) | p = 0.003 |
| 2 | 0 (0%) | 24 (17%) | |
| 3 | 5 @ (8%) | 9 (6%) | |
| Lesion Position | |||
| Proximal | 10 (16%) | 13 (9%) | p = 0.13 |
| Distal | 52 (84%) | 133 (91%) | |
| Duration of symptoms prior to diagnosis* | |||
| ≤ 75 days | 46 (78%) | 110 (77%) | p = 0.92 |
| > 75 days | 13 (22%) | 32 (23%) | |
| Positive margins # | |||
| No | 23 (48%) | 15 (19%) | p<0.001 |
| Yes | 25 (52%) | 65 (81%) | |
| Major surgery & | |||
| No | 25 (49%) | 25 (30%) | p = 0.03 |
| Yes | 26 (51%) | 57 (70%) | |
@ 1 patient with an oedematous lesion, 3 patients with 2 lesions and 1 patient with 13 lesions
*n = 200 (missing data in 7 patients)
#n = 128
&n = 133