Table 3. Characteristics of patients who failed short-course antibiotic treatment for M. ulcerans infection.
Year | Age/Sex | Co-morbid | Lesion | Sx | Abx | Days | Cessation reason | Result |
---|---|---|---|---|---|---|---|---|
2001 | 79F | Diabetes | Distal leg ulcer | No | ClarithromycinEthambutol | 7 | Nausea | Local recurrence |
2002 | 73F | Diabetes I/S^ | Distal wrist nodule | No | Rifampicin Clarithromycin Ethambutol | 21 | Hepatitis | Local recurrence |
2006 | 94F | Nil noted | Distal leg ulcer | Yes* | Rifampicin Ciprofloxacin | 6 | Nausea / diarrhoea | Local and distal (ankle) recurrence |
Sx = surgery; Abx = antibiotics
^Immunosuppressed on prednisolone for eczema
*positive surgical margin