Skip to main content
. 2015 Feb 6;10(2):e0117008. doi: 10.1371/journal.pone.0117008

Fig 3. Altered PI3K signalling pathway, lipogenesis, and gluconeogenesis upon HFHS dieting.

Fig 3

The experiments were performed the same as described in the legend to Fig. 2. (A) Western blots of PI3Kp85, phospho-Akt (pAkt), Akt, phospho-FoxO1 (pFoxO1) and FoxO1 in the liver. (B) Western blots of phospho-Akt (pAkt), Akt, and PI3Kp85 in hypothalamus. (C) Western blots of LXRα, SREBP1c, PEPCK, phospho-GSK3α/β (pGSK3α/β), and GSK3β in the liver. § P<0.05 relative to basal (0 week). * P<0.05, ** P<0.01 between HFHS diet versus chow diet conditions.