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. 2014 Dec 11;49(11):1022–1032. doi: 10.1310/hpj4911-1022

Table 1. Demographic and clinical characteristics of study subjects.

Characteristic IV APAP (n = 88) Not given IV APAP (n = 88) P
Mean age, years (±SD) 62.3 (12.8) 61.6 (11.9) .696

Female, n (%) 33 (37.5) 33 (37.5) 1

Mean weight, kg (±SD) 89.4 (24.5) 86 (21.1) .319

Race, n (%)
 Caucasian 67 (76.1) 73 (82.9) .246
 African American 20 (22.7) 13 (14.8)
 Other 1 (1.1) 2 (2.3)

Type of procedure, n (%)
 Hip replacement 51 (58) 38 (43.2) .07
 Knee replacement 37 (42) 50 (56.8)

Opioid tolerance, n (%)a 3 (3.4) 1 (1.1) .62

Note: IV APAP = intravenous acetaminophen.

a

Opioid tolerance defined as using ≥60 mg of oral morphine equivalents per day before undergoing hip or knee replacement.