Table 1. Demographic and clinical characteristics of study subjects.
Characteristic | IV APAP (n = 88) | Not given IV APAP (n = 88) | P |
Mean age, years (±SD) | 62.3 (12.8) | 61.6 (11.9) | .696 |
Female, n (%) | 33 (37.5) | 33 (37.5) | 1 |
Mean weight, kg (±SD) | 89.4 (24.5) | 86 (21.1) | .319 |
Race, n (%) | |||
Caucasian | 67 (76.1) | 73 (82.9) | .246 |
African American | 20 (22.7) | 13 (14.8) | – |
Other | 1 (1.1) | 2 (2.3) | – |
Type of procedure, n (%) | |||
Hip replacement | 51 (58) | 38 (43.2) | .07 |
Knee replacement | 37 (42) | 50 (56.8) | – |
Opioid tolerance, n (%)a | 3 (3.4) | 1 (1.1) | .62 |
Note: IV APAP = intravenous acetaminophen.
Opioid tolerance defined as using ≥60 mg of oral morphine equivalents per day before undergoing hip or knee replacement.