Table 2. Primary and secondary outcome measures.
| Factor or measure | IV APAP (n = 88) | Not given IV APAP (n = 88) | P |
| 24-hour postoperative opioid consumption, mg | |||
| Mean opioid consumption (±SD)a | 149.3 (98.7) | 147.2 (122.6) | .904 |
| Median opioid consumption (range)a | 132.1 (0-446.5) | 118.4 (0-741) | – |
| PACU time, min | |||
| Mean PACU time (±SD) | 163.1 (74.6) | 169.4 (78.2) | .588 |
| Median PACU time (range; min) | 149 (45-450) | 162 (60-494) | – |
| Safety endpoints, n (%) | |||
| Patients with RASS score ≤ -4 | 0 (0) | 0 (0) | – |
| Patients requiring naloxone bolus | 0 (0) | 0 (0) | – |
Note: IV APAP = intravenous acetaminophen; PACU = postanesthesia care unit; RASS = Richmond Agitation and Sedation Scale.
a
In oral morphine equivalents.