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. 2014 Dec 11;49(11):1022–1032. doi: 10.1310/hpj4911-1022

Table 3. Adjunctive analgesic utilization during 24-hour post-operative period, n/N (%).

Adjunctive analgesic IV APAPa (n = 88) Not given IV APAP (n = 88) P
Oral acetaminophen 57 (64.8) 58 (65.9) 1
 Hip 25/51 (49) 24/38 (63.2) .203
 Knee 32/37 (86.5) 34/50 (68) .075

Celecoxib 34 (38.6) 44 (50) .172
 Hip 11/51 (21.6) 12/38 (31.6) .333
 Knee 23/37 (62.2) 32/50 (64) 1

Bupivacaine 20 (22.7) 31 (35.2) .096
 Hip 17/51 (33.3) 25/38 (65.8) .003
 Knee 3/37 (8.1) 6/50 (12) .727

Ropivacaine 32 (36.4) 42 (47.7) .169
 Hip 0/51 (0) 2/38 (5.3) .18
 Knee 32/37 (86.5) 40/50 (80) .569

Gabapentin or pregabalin 26 (29.5) 47 (53.4) .002
 Hip 8/51 (15.7) 12/38 (31.6) .122
 Knee 18/37 (48.6) 35/50 (70) .049

NSAIDs (oral or IV) 3 (3.4) 4 (4.5) 1
 Hip 3/51 (5.9) 2/38 (5.3) 1
 Knee 0/37 (0) 2/50 (4) .501

Tramadol 2 (2.2) 2 (2.2) 1
 Hip 1/51 (2) 0/38 (0) 1
 Knee 1/37 (2.7) 2/50 (4) 1

Note: APAP = acetaminophen; IV = intravenous; NSAIDs = nonsteroidal anti-inflammatory drugs (nonselective agents only).