Table 4. Sequence, epigenetic and gene characteristics of conserved (n = 6) replication U-domain borders of H1hesc that switch from state ECi to Cj.

	Nb	GC	CpGo/e	H2AZ	CTCF	NANOG	OCT4	DHS	Promoters/border	Expressed promoters/border
1 to 1	38	0.445	0.233	0.331	0.663	1.321	0.335	0.016	3.947	3.237
1 to 2	3	0.458	0.235	0.346	0.472	0.733	0.145	0.018	3.333	3
2 to 1	4	0.444	0.198	1.214	1.066	1.254	0.133	0.025	3	1.75
2 to 2	6	0.427	0.206	0.606	0.872	0.556	0.458	0.021	2.667	2
2 to 3	1	0.436	0.179	0.468	0.248	0.277	0	0.014	2	2
3 to 2	1	0.418	0.16	0.765	0.419	0	0	0.008	3	3
4 to 2	1	0.391	0.143	0.526	0.261	0	0	0	2	2
4 to 3	1	0.445	0.192	1.227	0.049	0.234	0	0.004	1	1

For each border type, the table provides number (Nb), G+C content (GC), coverage by significantly enriched intervals relative to the genome average coverage for H2AZ (genome average 33%), CTCF (4.5%), NANOG (0.2%) and OCT4 (0.07%), coverage by DNase I hypersensitive sites (DHS), as well as the numbers of promoters and expressed promoters per border.