Table 1. Summary of protein expression and subcellular localization for RanBPM mutants.
Mutant | Expression | Subcellular Localization |
---|---|---|
WT | *** | N = C |
ΔC1 | *** | N = C |
ΔC2 | *** | N = C |
ΔC3 | *** | N = C |
ΔC4 | *** | N = C |
ΔN1 | * | N>C |
ΔN2 | ** | C>N |
ΔN3 | * | N>C |
ΔN4 | * | N>C |
Δ1-66 | *** | C>N |
Δ1-25 | *** | C>N |
Δ212 | *** | N>C |
Δ360 | *** | N>C |
ΔLisH | *** | N = C |
ΔCTLH | *** | N>C |
NLS1 Mut (150, 152, 153) | *** | N>C |
NES Mut (147, 151) | *** | N>C |
NLS2 Mut (635, 636, 640) | *** | N = C |
*low, **medium ***high expression, N = C nucleocytoplasmic, N>C mostly nuclear, C>N mostly cytoplasmic