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. 2014 Dec 22;8(2):133–148. doi: 10.1111/eva.12237

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© 2014 Her Majesty the Queen in Right of Canada. Evolutionary Applications published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Expression of genes potentially related to resistance in Atlantic lice. (A) The expression of peroxidasin homolog (pxdn) was highly overexpressed in the resistant population for both sexes, and (B) zinc metalloproteinase nas-14 (nas-14) was specifically overexpressed in resistant males. (C) In contrast to the strong differences between populations, the effect of emamectin benzoate dose was minor, although several genes were differentially expressed, including kynurenine-3 monooxygenase (kmo). (D) As identified in previous candidate gene approaches, here, p-glycoprotein (pgp) was overexpressed in the resistant population and had highest expression in males. Data in (A–C) are from the microarray and (D) RT-qPCR.