Table 2. Distribution of serum bone markers by CKD stage.
| All | p | CKD Stage | |||
|---|---|---|---|---|---|
| 3 | 4 | 5 | |||
| BAP (U/L) | 147 ± 84 | 146 ± 74 | 151 ± 92 | 127 ± 73 | |
| BAP SDS | 1.25 ± 2.06 | <0.0001 | 1.27 ± 1.75 | 1.28 ± 2.27 | 0.91 ± 2.14 |
| TRAP5b (U/L) | 13.1 ± 6.6 | 13.3 ± 6.1 | 13.0 ± 7.0 | 12.8 ± 6.6 | |
| TRAP5b SDS | 0.13 ± 1.56 | 0.05 | 0.18 ± 1.35 | 0.10 ± 1.69 | 0.16 ± 1.7 |
| Sclerostin (μg/L) | 0.31 ± 0.12 | 0.30 ± 0.12 | 0.31 ± 0.12 | 0.33 ± 0.16 | |
| Sclerostin SDS | -0.99 ± 1.17 | <0.0001 | -1.05 ± 1.16 | -0.94 ± 1.12 | -1.0 ± 1.6 |
| cCFGF-23 (kRU/L) | 183 (112, 321) | 128 (89, 221) A | 226 (136, 355) B | 654 (321, 1224) B | |
| cCFGF-23 SDS | 3.21 (1.43, 5.46) | <0.0001 | 1.76 (0.67, 3.81) A | 3.85 (1.95, 6.12) B | 7.85 (4.94, 14.3) C |
Data are given as mean ± SD or median (interquartile range) P values indicate difference of age- and sex-adjusted SDS from reference population. Different superscript letters indicate significant differences (p<0.05) between CKD stages (according to ANOVA using Student-Newman-Keuls grouping).
A, B & C: Student-Newman-Keuls Grouping—Means with the same letter are not significantly different.