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. 2015 Feb 6;10(2):e0116748. doi: 10.1371/journal.pone.0116748

Fig 2. Treatment with CR-1 induces expression of CR-1 through ALK4/SMAD2/3 pathway.

Fig 2

(a) Western blot to detect phosphorylation of SMAD2 in U-87 MG cells treated with different combinations of CR1-GST, GST and ALK4 inhibitor (SB-431542) for 15 min. (b) RT-PCR to check expression of CR-1 after 24 hr treatment of U-87 MG cells with different combinations of CR1-GST and SB-431542.