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. 2015 Feb 6;10(2):e0117007. doi: 10.1371/journal.pone.0117007

Table 3. Stratification analysis of the miRNA polymorphisms.

Characteristics rs2910164 rs11614913
Control* Case* ORadd (95% CI) P add P interaction Control* Case* ORadd (95% CI) P add P interaction
Age
< = 60 112/121/30 84/107/35 1.30 (0.95–1.76) 0.097 70/128/65 69/112/45 0.91 (0.68–1.22) 0.528
>60 107/136/25 105/154/46 1.40 (1.06–1.86) 0.020 0.628 83/138/47 97/153/55 0.96 (0.74–1.26) 0.789 0.564
Sex
Male 133/168/26 131/160/36 1.17 (0.89–1.54) 0.267 96/155/76 96/170/61 0.89 (0.69–1.13) 0.338
Female 86/89/29 58/101/45 1.65 (1.21–2.26) 0.002 0.122 57/111/36 70/95/39 0.95 (0.69–1.30) 0.756 0.773
Smoking
No 150/183/45 123/183/56 1.29 (1.00–1.66) 0.048 111/191/76 107/185/70 1.02 (0.80–1.31) 0.848
Yes 69/74/10 66/78/25 1.56 (1.08–2.26) 0.018 0.323 42/75/36 59/80/30 0.75 (0.54–1.05) 0.093 0.133
Drinking
No 182/203/46 145/216/69 1.44 (1.15–1.82) 0.002 123/223/85 139/213/78 0.88 (0.70–1.10) 0.235
Yes 37/54/9 44/45/12 1.08 (0.67–1.74) 0.753 0.206 30/43/27 27/52/22 1.06 (0.69–1.62) 0.802 0.479
Hypertension
No 172/197/47 68/91/32 1.34 (1.03–1.74) 0.029 124/206/86 58/93/40 1.01 (0.78–1.30) 0.952
Yes 47/60/8 121/170/49 1.38 (0.98–1.93) 0.062 0.814 29/60/26 108/172/60 0.77 (0.56–1.05) 0.099 0.233
Diabetes mellitus
No 194/238/53 138/194/65 1.30 (1.04–1.62) 0.019 142/238/105 124/198/75 0.91 (0.74–1.13) 0.393
Yes 25/19/2 51/67/16 1.78 (0.97–3.25) 0.063 0.296 11/28/7 42/67/25 0.92 (0.54–1.58) 0.766 0.974

*Wild-type homozygote/heterozygote/variant homozygote.

†Additive model (wild-type homozygote vs. heterozygote vs. variant homozygote). Data were calculated by unconditional logistic regression, adjusted for age, sex, smoking, drinking, BMI, hypertension and diabetes mellitus.