Table II.
Sample Characteristics.
| Variable (units) | All Patients Mean (SD) (n=70) |
Younger Cohort Mean (SD) (n=30) |
Older Cohort Mean (SD) (n=40) |
|---|---|---|---|
| HAND | 1.24 (1.40) | 1.20 (1.32) | 1.28 (1.47) |
| GDS | 0.74 (0.62) | 0.85 (0.64) | 0.65 (0.59) |
| HDS | 12.2 (3.1) | 12.7 (2.7) | 11.8 (3.3) |
| Years infected (years) | 18.61 (6.43) | 17.70 (6.79) | 19.30 (6.14) |
| Age (years) | 53.7 (10.0) | 43.9 (5.6) | 61.1 (4.6) |
| Absolute CD4+ count (cells/mm3) | 411.46 (303.55) | 299.87 (241.11) | 495.15 (320.98) |
| Plasma viral load (IU/L) | 14,036.14 (50,163.34) | 23,994.63 (62,103.08) | 6,567.05 (38,087.31) |
| Nadir CD4+ count (cells/mm3) | 202.01 (211.69) | 134.47 (143.26) | 252.68 (240.59) |
| Bld Hemoglobin (g/L) | 13.8 (1.8) | 13.4 (2.2) | 14.1 (1.5) |
| BDI | 11.76 (9.47) | 13.53 (11.03) | 10.43 (8.00) |
| # Comorbidities | 2.41 (1.65) | 2.07 (1.28) | 2.68 (1.85) |
| Variable | All Patients (%) | Younger Cohort (%) | Older Cohort (%) |
|---|---|---|---|
| HCV | 25.7 | 20.0 | 30.0 |
| Chronic renal disease | 13.2 | 10.0 | 15.8 |
| Lipodystrophy | 27.5 | 20.1 | 32.5 |
| Tobacco smoking | 48.6 | 46.7 | 55.0 |
| Hypertension | 50.7 | 40.0 | 59.0 |
| Diabetes | 21.7 | 23.3 | 20.5 |
| Cardiovascular | 24.6 | 24.1 | 25.0 |
| Liver disease | 7.1 | 3.3 | 10.0 |
| Cerebrovascular | 10.4 | 13.8 | 7.8 |
| Hyperlipidemia | 39.1 | 26.7 | 48.7 |
| Cocaine/Meth | 8.5 | 3.3 | 12.5 |
| Race | |||
| Black | 34.3 | 40.0 | 30.0 |
| Hispanie (Caucasian) | 17.1 | 30.0 | 7.5 |
| White | 38.6 | 23.3 | 50.0 |
| Other (Native American) | 10.0 | 6.7 | 12.5 |
| Gender | |||
| Male | 84.3 | 90.0 | 80.0 |
| Female | 15.7 | 10.0 | 20.0 |