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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Gene Ther. 2014 Nov 27;22(2):138–145. doi: 10.1038/gt.2014.105

Figure 2.

Figure 2

AAV2-Hsp70 protects RGCs from axonal injury. A. Representative images of Rbpms-labeled RGCs in uninjured and ONC retinas. RGC densities in mice with no ONC damage were similar in vehicle (PBS)-injected and AAV2-Hsp70-injected animals. The number of RGCs two weeks after ONC was reduced by approximately 80% compared to uninjured controls. B. Quantitative analysis of RGCs in whole mount retinas showed approximately 110% increase in cell survival in animals injected with AAV2-Hsp70 two weeks after ONC compared to vehicle-injected ONC control group (*P=0.029).