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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Gene Ther. 2014 Nov 27;22(2):138–145. doi: 10.1038/gt.2014.105

Figure 4.

Figure 4

RGC density in vehicle- and 17-AAG-treated animals. A. Representative images of flat mounted rat retinas used for quantification of RGCs. RGCs immunolabeled with Rbpms antibodies were counted in three sampling fields (0.32 X 0.24 mm each) within the superior, temporal, inferior and nasal retinal quadrants at 1, 2, 3 and 4 mm from the optic disc. B. Two weeks after ONC, RGC density in vehicle-treated rats was decreased approximately 80% compared to the uninjured vehicle-treated animals. The number of surviving RGCs in retinas of 17-AAG/ONC animals was approximately 49% higher than in Vehicle/ONC retinas (*P=0.007).