Table 3.

Differential brain activation to addition versus subtraction problems in DD and TD children

Region	Cluster size (voxels)	Peak z-score	Peak MNI coordinates
			x	y	z
Addition > Subtraction
Right STG/MTG/ hippocampus	715	3.64	50	−4	−20
Left STG	145	3.21	−44	−6	−14
Left hippocampus	242	3.10	−34	−18	−18
Subtraction > Addition
Right SMG	143	3.40	58	−36	54
Left SMG/IPS	157	3.07	−48	−46	58
Left MFG	240	3.01	−40	4	36

DD = Developmental Dyscalculia, TD = Typically Developing, STG = Superior Temporal Gyrus, MTG = Middle Frontal Gyrus, SMG = SupraMarginal Gyrus, IPS = IntraParietal Sulcus, MFG = Middle Frontal Gyrus. Regions significant at height threshold of p < .01, corrected for multiple comparisons at p < .01 which corresponds to cluster extent of 128 voxels after gray matter masking. Voxel size is 2 mm³.