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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Nucl Med. 2014 May 15;55(7):1138–1143. doi: 10.2967/jnumed.114.139170

Figure 1.

Figure 1

A three compartment model was used to describe the kinetic distribution of 18F− ions to tumor and bone. K1 is the transfer rate of 18F− from the first compartment 1 (plasma) to compartment 2 (extracellular fluid space) in units of mL/min/g, k2 is the transfer rate from 2 to 1 (1/min), k3 is the transfer rate from 2 to compartment 3 (hydroxyapatite lattice) in units of 1/min, and k4 is the transfer rate. from 3 to 2 (1/min).