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Somatic hypermutation frequencies and CDR3 lengths are not significantly different between HIV-1 Env-reactive IgG antibodies in blood and colostrum.
| Nonreactive | HIV-1 Env-reactive | p-value | ||
|---|---|---|---|---|
| Mean CDR3 length (amino acids) | Blood | 15 | 16 | 0.83 |
| Colostrum | 17 | 17 | 0.94 | |
|
|
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| p-valuea | 0.12 | 0.13 | ||
|
| ||||
| Mean mutation frequency (%) | Blood | 6 | 6 | 0.97 |
| Colostrum | 6 | 7 | 0.24 | |
|
|
||||
| p-value | 0.90 | 0.21 | ||
Analyses performed using linear mixed model; p > 0.05 is not significant.
