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. Author manuscript; available in PMC: 2016 Mar 1.

Published in final edited form as: J Mol Neurosci. 2014 Aug 26;55(3):644–652. doi: 10.1007/s12031-014-0403-7

Fig.7 — The interaction of SF and obesity on locomotor activities. (A) Effect of POKO and sex difference on open field performance. All male and female POKO mice had fewer outer and inner grids crossed and less rearing than their respective WT mice. Female WT mice also showed more outer grids crossed than the male WT mice. (B) There was also an increase of fecal and urine production in the POKO mice. (C) In the SF study, a significant strain effect was seen (p < 0.005), as POKO mice crossed fewer total grids than the WT mice. Post-hoc analysis showed that SF reduced activity in the WT mice (p < 0.05) but not the POKO mice which showed a lower baseline.

Fig.7 — The interaction of SF and obesity on locomotor activities. (A) Effect of POKO and sex difference on open field performance. All male and female POKO mice had fewer outer and inner grids crossed and less rearing than their respective WT mice. Female WT mice also showed more outer grids crossed than the male WT mice. (B) There was also an increase of fecal and urine production in the POKO mice. (C) In the SF study, a significant strain effect was seen (p < 0.005), as POKO mice crossed fewer total grids than the WT mice. Post-hoc analysis showed that SF reduced activity in the WT mice (p < 0.05) but not the POKO mice which showed a lower baseline.