Table 1. Characteristics of the 11 studies included in the meta-analysis.
Author | Nation | Year | FS | B value | De | Blind | RS | TI | No. HCCs | Age | Size | TH | TP | FP | FN | TN | W/P | Inter |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chang et al | Taiwan | 2014 | 1.5 | 0,500 | retro | Yes | S | 9.4 | 141 | 61.9 | 3.73 | 1.7 | 28 | 18 | 6 | 89 | W | ADC-Q |
Taiwan | 2014 | 1.5 | 0,500 | retro | Yes | S | 9.4 | 141 | 61.9 | 3.73 | 1.4 | 36 | 10 | 7 | 88 | P | ADC-Q | |
Woo et al | Korea | 2013 | 3 | 0,25,50,75,100,200,500,800 | retro | Yes | S | 17 | 42 | 55.5 | 4.7 | 1.14 | 13 | 6 | 5 | 18 | P | ADC-Q |
Sandrasegaran et al | USA | 2012 | 1.5 | 0,50,400,500, 800 | retro | Yes | B | ? | 41 | 55 | 4.4 | 0.99 | 12 | 4 | 2 | 23 | W | ADC-Q |
USA | 2012 | 1.5 | 0, 50 | retro | Yes | B | ? | 41 | 55 | 4.4 | — | 5 | 4 | 9 | 23 | W | VA | |
An et al | Korea | 2012 | 3 | 0,50,400,800 | retro | Yes | S | ? | 201 | 57 | 2.7 | — | 23 | 8 | 14 | 156 | W | VA |
Korea | 2012 | 3 | 0, 50, 400, 800 | retro | Yes | S | ? | 201 | 57 | 2.7 | — | 33 | 137 | 1 | 30 | P | VA | |
Saito et al | Japan | 2012 | 1.5 | 100,800 | retro | Yes | B | ? | 42 | 69 | 1.83 | — | 13 | 2 | 4 | 23 | W | VA |
Japan | 2012 | 1.5 | 100, 800 | retro | Yes | B | ? | 42 | 69 | 1.83 | — | 7 | 20 | 0 | 15 | P | VA | |
Nakanishi et al | Japan | 2012 | 1.5 | 50,1000 | retro | Unclear | S | <30 | 50 | 61 | 5.7 | 0.8 | 14 | 6 | 4 | 26 | P | ADC-Q |
Nishie et al | Japan | 2011 | 1.5 | 0,500,1000 | retro | Unclear | S | <30 | 85 | 65 | 3.6 | 0.972 | 19 | 16 | 7 | 43 | P | ADC-Q |
Heo et al | Korea | 2010 | 1.5 | 0,1000 | retro | Yes | S | 11 | 27 | 57 | 5.6 | 0.99 | 7 | 3 | 2 | 15 | P | ADC-Q |
Muhi et al | Japan | 2009 | 1.5 | 500,1000 | retro | Yes | B | 8 | 86 | 62.7 | 2.4 | 0.92 | 25 | 4 | 14 | 43 | W | ADC-Q |
Nasu et al | Japan | 2009 | 1.5 | 0,500 | retro | Unclear | S | 18.3 | 125 | 64.8 | 2.9 | — | 3 | 8 | 22 | 92 | W | VA |
Japan | 2009 | 1.5 | 0,500 | retro | Unclear | S | 18.3 | 125 | 64.8 | 2.9 | — | 33 | 54 | 6 | 32 | P | VA | |
Piana et al | France | 2011 | 1.5 | 0, 500 | retro | Yes | B | 45 | 72 | 63 | 2.2 | — | 7 | 4 | 28 | 33 | W | VA |
France | 2011 | 1.5 | 0, 500 | retro | Yes | B | 45 | 72 | 63 | 2.2 | — | 8 | 53 | 1 | 10 | P | VA |
FS, field strength (Tesla); De, design; RS, reference standard (S, surgical specimens; B, biopsy or surgical specimens); TI, time intervals between DWI and reference standard (days); TH, the diagnostic threshold of ADC (×10﹣3mm2/s); TP, true positive; FP, false positive; FN, false negative; TN, true negative; W, the prediction of well-differentiated HCC; P, the prediction of poorly-differentiated HCC; Inter, image interpretation; ADC-Q, ADC quantification; VA, visual assessment.