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. 2015 Feb 6;10(2):e0117661. doi: 10.1371/journal.pone.0117661

Table 1. Characteristics of the 11 studies included in the meta-analysis.

Author Nation Year FS B value De Blind RS TI No. HCCs Age Size TH TP FP FN TN W/P Inter
Chang et al Taiwan 2014 1.5 0,500 retro Yes S 9.4 141 61.9 3.73 1.7 28 18 6 89 W ADC-Q
Taiwan 2014 1.5 0,500 retro Yes S 9.4 141 61.9 3.73 1.4 36 10 7 88 P ADC-Q
Woo et al Korea 2013 3 0,25,50,75,100,200,500,800 retro Yes S 17 42 55.5 4.7 1.14 13 6 5 18 P ADC-Q
Sandrasegaran et al USA 2012 1.5 0,50,400,500, 800 retro Yes B ? 41 55 4.4 0.99 12 4 2 23 W ADC-Q
USA 2012 1.5 0, 50 retro Yes B ? 41 55 4.4 5 4 9 23 W VA
An et al Korea 2012 3 0,50,400,800 retro Yes S ? 201 57 2.7 23 8 14 156 W VA
Korea 2012 3 0, 50, 400, 800 retro Yes S ? 201 57 2.7 33 137 1 30 P VA
Saito et al Japan 2012 1.5 100,800 retro Yes B ? 42 69 1.83 13 2 4 23 W VA
Japan 2012 1.5 100, 800 retro Yes B ? 42 69 1.83 7 20 0 15 P VA
Nakanishi et al Japan 2012 1.5 50,1000 retro Unclear S <30 50 61 5.7 0.8 14 6 4 26 P ADC-Q
Nishie et al Japan 2011 1.5 0,500,1000 retro Unclear S <30 85 65 3.6 0.972 19 16 7 43 P ADC-Q
Heo et al Korea 2010 1.5 0,1000 retro Yes S 11 27 57 5.6 0.99 7 3 2 15 P ADC-Q
Muhi et al Japan 2009 1.5 500,1000 retro Yes B 8 86 62.7 2.4 0.92 25 4 14 43 W ADC-Q
Nasu et al Japan 2009 1.5 0,500 retro Unclear S 18.3 125 64.8 2.9 3 8 22 92 W VA
Japan 2009 1.5 0,500 retro Unclear S 18.3 125 64.8 2.9 33 54 6 32 P VA
Piana et al France 2011 1.5 0, 500 retro Yes B 45 72 63 2.2 7 4 28 33 W VA
France 2011 1.5 0, 500 retro Yes B 45 72 63 2.2 8 53 1 10 P VA

FS, field strength (Tesla); De, design; RS, reference standard (S, surgical specimens; B, biopsy or surgical specimens); TI, time intervals between DWI and reference standard (days); TH, the diagnostic threshold of ADC (×10﹣3mm2/s); TP, true positive; FP, false positive; FN, false negative; TN, true negative; W, the prediction of well-differentiated HCC; P, the prediction of poorly-differentiated HCC; Inter, image interpretation; ADC-Q, ADC quantification; VA, visual assessment.