Table 1. The Pharmaceutical Value Chain [17].
Early Stage Discovery | Late Stage Discovery | Clinical Trials | Regulatory Approval | |
---|---|---|---|---|
Description | Basic research (i.e., undirected research into the mechanisms that cause disease) and target identification and validation (i.e., identifying and validating points where drugs can intervene to disrupt disease) | Finding and optimizing lead compounds to ensure that they possess the properties needed to make an effective drug. | Determining the efficacy and safety of a drug/vaccine in people | Securing governmental authorization to sell a drug/vaccine |