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. 2015 Feb 6;10(2):e0116644. doi: 10.1371/journal.pone.0116644

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Fig 8 — We determined the expression of the genes GPNMB and SPP1 in CD11b⁺ and CD11b^- cells isolated from human GBM (CD11b⁺ n = 15, CD11b^- n = 9), meningioma (CD11b⁺ n = 5, CD11b^- n = 3), grade III anaplastic astrocytoma (CD11b⁺ n = 2, CD11b^- n = 2), control brain (CD11b⁺ n = 5, CD11b^- n = 2) and blood monocyte samples (n = 2). The expression of GPNMB and SPP1 was significantly higher in CD11b⁺ cells isolated from GBMs compared to CD11b⁺ cells isolated from control brain, benign meningioma samples, blood monocytes, and CD11b^- cells in GBM. Bar graphs illustrate the absolute number of transcripts normalized to 100,000 transcripts of ACTB. Analysis was done by students t test. Error bars indicate the SEM. *, p<0.05; **, p<0.01; ***, p<0.001