Table 1. The 25 highest-upregulated genes in the glioma-associated data set compared to all three control sets.

			Log2 Expression
Gene Symbol	Module	P Value	GAMs	Naïve Microglia	Control Mϕ1	Control Mϕ2	Fold Change
Gpnmb	red	2.06E-07	12.63	7.26	7.60	7.51	36.02
Cxcl9	red	1.69E-08	12.83	7.63	7.14	8.67	32.27
Spp1	red	7.59E-06	12.31	7.92	7.84	6.88	27.24
Ly6i	red	6.84E-09	11.55	6.94	6.79	7.07	24.48
Gjc3	red	1.41E-08	11.62	7.74	6.97	7.13	20.32
Il1r2	red	1.86E-06	11.64	8.22	7.03	6.99	18.70
Cd72	red	1.63E-06	12.13	8.81	7.63	7.42	18.04
Ms4a4c	red	2.36E-07	12.11	7.72	8.00	8.15	17.76
Mmp13	red	2.34E-07	11.08	7.11	6.77	6.91	17.73
Serpina3n	red	3.08E-08	11.71	8.18	7.17	7.39	17.45
Ptgs2	orange	0.001883	12.61	11.09	7.167	7.23	17.28
Gpr171	red	1.02E-07	11.23	7.20	7.21	7.24	16.12
Igfbp7	orange	0.00065	12.52	10.53	7.59	7.49	15.83
Il1b	orange	0.001877	12.71	11.25	7.42	7.58	15.54
Ccl5	red	1.58E-10	12.46	9.02	8.00	8.64	15.03
Adamdec1	red	2.47E-07	10.69	6.75	6.81	6.84	14.78
Il1rn	red	1.99E-10	11.63	8.03	7.46	7.77	14.76
Ifi44	red	3.59E-07	11.42	7.53	7.27	7.95	14.32
Spon1	red	4.10E-07	11.77	8.72	7.52	7.55	14.30
Acp5	brown	0.000145	12.38	7.74	9.24	8.88	13.58
Moxd1	red	4.40E-08	10.83	7.21	7.15	7.11	12.77
Trem1	red	7.96E-07	11.43	8.10	7.65	7.57	12.62
Gm6377	red	2.25E-06	11.14	8.45	7.05	7.02	12.40
Vcam1	orange	0.000315	11.76	9.95	7.19	7.36	12.12
Dnase1l3	brown	0.000265	10.98	6.91	7.68	7.66	11.84