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. Author manuscript; available in PMC: 2016 Jan 31.

Published in final edited form as: Genet Epidemiol. 2014 Dec 23;39(2):134–143. doi: 10.1002/gepi.21875

Table 1.

16 mediation genes of miR-223.

	Gene	P-value of ME		AE of miR-223^*	95% CI^*		P-value of AE^*	ME^*	95% CI^*		P-value of ME^*
	Gene	Discovery Set	Validation Set	AE of miR-223^*	95% CI^*		P-value of AE^*	ME^*	95% CI^*		P-value of ME^*
1	NFKBIZ	0.0041	0.0010	3.44	1.32	8.99	0.012	0.29	0.17	0.50	7.8E-06
2	PSCD4	0.0029	0.0025	2.90	1.14	7.38	0.025	0.30	0.18	0.51	8.9E-06
3	BCL3	0.0043	0.0017	2.90	1.14	7.36	0.025	0.31	0.19	0.53	1.1E-05
4	SLC16A3	0.00047	0.016	2.42	0.99	5.90	0.053	0.36	0.23	0.58	1.6E-05
5	PLEKHQ1	0.0021	0.0089	2.41	0.98	5.93	0.056	0.37	0.23	0.59	2.9E-05
6	LHFPL2	0.0029	0.010	2.56	1.00	6.57	0.051	0.33	0.20	0.56	4.1E-05
7	LSP1	0.00055	0.030	2.00	0.83	4.82	0.12	0.46	0.32	0.67	5.0E-05
8	URP2	0.0052	0.0088	2.21	0.88	5.56	0.090	0.35	0.21	0.58	5.7E-05
9	CTSL1	0.0024	0.0097	2.30	0.92	5.74	0.075	0.36	0.22	0.60	6.6E-05
10	ISG20	0.0068	0.017	1.73	0.74	4.04	0.21	0.52	0.37	0.74	0.00020
11	HMOX1	0.0038	0.034	1.88	0.77	4.56	0.16	0.45	0.29	0.68	0.00021
12	IL17RA	0.0079	0.039	1.58	0.68	3.70	0.29	0.53	0.37	0.74	0.00026
13	RBMX	0.0077	0.039	1.78	0.74	4.25	0.20	0.52	0.37	0.74	0.00027
14	FZD7	0.0031	0.048	1.55	0.66	3.66	0.32	0.52	0.36	0.74	0.00030
15	CCNB1IP1	0.0070	0.036	1.76	0.74	4.16	0.20	0.54	0.38	0.75	0.00030
16	LITAF	0.0048	0.050	1.67	0.71	3.95	0.24	0.54	0.39	0.76	0.00030

^*

For total subjects.