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. 2005 Sep 21;11(35):5540–5544. doi: 10.3748/wjg.v11.i35.5540

Table 1.

Patients’ characteristics

n = 95 patients
Female:male 58:37 patients
Age (yr) 43 years (range 20–74 yr)
UC:CD 42:53 patients
Duration of IBD at start 6-TG 10.4 yr (SD 9.4 yr)
AZA intolerance 78 patients (82%)
6-MP intolerance 4 patients (4%)
AZA and 6-MP intolerance 13 patients (14%)
AZA or 6-MP rechallenge 36 patients (38%)
Adverse events on AZA or 6MP: 30% gastrointestinal complaints
20% general malaise
14% allergic reactions
10% pancreaticotoxicity
6% hepatotoxicity
5% myelotoxicity
14% rest (e.g., myalgia or alopecia)
6-TG dosage at the start 24.6 mg (range 20-40 mg)