Table 1.
Effect of chitosan nanoparticles on cell cycle of MGC803 cells (mean±SD)
Concentration (μg/mL) |
Cell cycle phase distribution (%) |
AI | ||
G0/G1 | S | G2/M | ||
0 | 71.8±1.3 | 17.3±0.9 | 9.5±0.2 | 1.7±0.2 |
25 | 70.5±0.8b | 16.7±1.1 | 8.3±2.1 | 3.9±0.6b |
50 | 69.4±0.6b | 15.9±0.6 | 7.4±0.3 | 6.8±0.3b |
75 | 67.3±0.4b | 13.2±2.3 | 12.3±0.5 | 7.6±0.4b |
100 | 51.5±1.3b | 23.5±1.1 | 15.2±3.1 | 9.9±0.5b |
AI: apoptotic incidence;
P<0.01 vs control.