Table 2.
List of genes downregulated by amygdalin treatment
| Gene | Chromosome | Title | Global M |
| Cell cycle | |||
| FRAP1 | 1p36.2 | FK506 binding protein 12-rapamycin associated protein 1 | –1.029 |
| TOP1 | 20q12–q13.1 | Topoisomerase (DNA) I | –1.118 |
| MRE11A | 11q21 | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | –1.235 |
| EXO1 | 1q42–q43 | Exonuclease 1 | –1.740 |
| ABCF2 | 7q36 | ABC, sub-family F (GCN20), member 2 | –1.993 |
| Cell growth | |||
| FRAP1 | 1p36.2 | FK506 binding protein 12-rapamycin associated protein 1 | –1.029 |
| TIEG2 | 2p25 | TGFB inducible early growth response 2 | –1.082 |
| NR3C2 | 4q31.1 | Nuclear receptor subfamily 3, group C, member 2 | –1.099 |
| IGF2R | 6q26 | Insulin-like growth factor 2 receptor | –1.011 |
| TOP1 | 20q12–q13.1 | Topoisomerase (DNA) I | –1.118 |
| MS4A2 | 11q13 | Membrane-spanning 4-domains, subfamily A, member 2 | –1.175 |
| (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | |||
| MRE11A | 11q21 | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | –1.235 |
| COPA | 1q23–q25 | Coatomer protein complex, subunit alpha | –1.304 |
| SORL1 | 11q23.2–q24.2 | Sortilin-related receptor, L (DLR class) A repeats-containing | –1.360 |
| NPC1 | 18q11–q12 | Niemann-Pick disease, type C1 | –1.405 |
| FGD1 | Xp11.21 | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | –1.518 |
| ABCF2 | 7q36 | ABC, sub-family F (GCN20), member 2 | –1.993 |
| EXO1 | 1q42–q43 | Exonuclease 1 | –1.740 |
| PLA2G1B | 12q23–q24.1 | Phospholipase A2, group IB (pancreas) | –2.293 |
| Stress response | |||
| IGF2R | 6q26 | Insulin-like growth factor 2 receptor | –1.011 |
| FRAP1 | 1p36.2 | FK506 binding protein 12-rapamycin associated protein 1 | –1.029 |
| TIEG2 | 2p25 | TGFB inducible early growth response 2 | –1.082 |
| NR3C2 | 4q31.1 | Nuclear receptor subfamily 3, group C, member 2 | –1.099 |
| TOP1 | 20q12–q13.1 | Topoisomerase (DNA) I | –1.118 |
| MS4A2 | 11q13 | Membrane-spanning 4-domains, subfamily A, member 2 | –1.175 |
| (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | |||
| MRE11A | 11q21 | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | –1.235 |
| COPA | 1q23-q25 | Coatomer protein complex, subunit alpha | –1.304 |
| SORL1 | 11q23.2–q24.2 | Sortilin-related receptor, L(DLR class) A repeats-containing | –1.360 |
| NPC1 | 18q11–q12 | Niemann-Pick disease, type C1 | –1.405 |
| FGD1 | Xp11.21 | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | –1.518 |
| EXO1 | 1q42–q43 | Exonuclease 1 | –1.740 |
| ABCF2 | 7q36 | ABC, sub-family F (GCN20), member 2 | –1.993 |
| PLA2G1B | 12q23–q24.1 | Phospholipase A2, group IB (pancreas) | –2.293 |
| Transcription | |||
| IGF2R | 6q26 | Insulin-like growth factor 2 receptor | –1.011 |
| FRAP1 | 1p36.2 | FK506 binding protein 12-rapamycin associated protein 1 | –1.029 |
| TIEG2 | 2p25 | TGFB inducible early growth response 2 | –1.082 |
| NR3C2 | 4q31.1 | Nuclear receptor subfamily 3, group C, member 2 | –1.099 |
| MS4A2 | 11q13 | Membrane-spanning 4-domains, subfamily A, member 2 | –1.175 |
| (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | |||
| TOP1 | 20q12–q13.1 | Topoisomerase (DNA) I | –1.118 |
| MRE11A | 11q21 | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | –1.235 |
| COPA | 1q23–q25 | Coatomer protein complex, subunit alpha | –1.304 |
| SORL1 | 11q23.2–q24.2 | Sortilin-related receptor, L (DLR class) A repeats-containing | –1.360 |
| NPC1 | 18q11–q12 | Niemann-Pick disease, type C1 | –1.405 |
| FGD1 | Xp11.21 | FYVE, RhoGEF, and PH domain containing 1 (faciogenital dysplasia) | –1.518 |
| ABCF2 | 7q36 | ABC, sub-family F (GCN20), member 2 | –1.993 |
| EXO1 | 1q42–q43 | Exonuclease 1 | –1.740 |
| PLA2G1B | 12q23–q24.1 | Phospholipase A2, group IB (pancreas) | –2.293 |