Figure 1.

Linoleic acid inhibits MPP ⁺ -induced cell death. Cultured PC12 cells were subjected to 500 μM MPP⁺ in the absence or presence of different concentrations of linoleic acid (LA) (1–100 μM) for 24 h at 37°C. Number of viable cells was determined by MTT assay. The control was set to 100% survival. Data are means ± SEM (n = 3). Data were analyzed using one-way ANOVA and Neuman-Keuls’ test. Means with superscripts ^a and ^b are significantly different at P < 0.05 comparing control and 500 μM MPP⁺ only-treated groups, respectively.