Figure 4.

Average meal size and meal frequency following I3vt leptin (4μg) and SC liraglutide (75μg/kg). SC liraglutide reduced meal size and meal frequency while I3vt leptin reduced meal frequency only. Co-administration of liraglutide and leptin reduced meal size and meal frequency but the meal size effect was not greater than liraglutide alone and the meal frequency effect was not different from either liraglutide or leptin. * P<0.05 vs I3vt Veh/SC Veh.