Table 2.

Association of baseline body composition measures and adipokines with annual eGFRCys change^* in HIV-infected FRAM participants (N = 554).

(results are per doubling)	Unadjusted Estimate (95%CI)	Adjusted Estimate (95%CI)** (single measures)
MRI-measured body composition:
VAT	0.22 (−0.10, 0.54) p=0.18	0.07 (−0.26, 0.41) p=0.67
Skeletal Muscle	0.18 (−1.62, 1.98) p=0.84	0.17 (−1.60, 1.93) p=0.85
Total Fat	0.10 (−0.36, 0.56) p=0.67	0.18 (−0.33, 0.69) p=0.50
Arm SAT	0.12 (−0.47, 0.71) p=0.69	0.24 (−0.43, 0.91) p=0.48
Leg SAT	0.05 (−0.36, 0.46) p=0.81	0.27 (−0.24, 0.79) p=0.30
Upper Trunk SAT	0.19 (−0.25, 0.64) p=0.39	0.22 (−0.26, 0.69) p=0.37
Lower Trunk SAT	−0.09 (−0.44, 0.27) p=0.64	−0.05 (−0.44, 0.35) p=0.81
Adipokines:
Adiponectin	−0.28 (−0.63, 0.080) p=0.13	−0.16 (−0.53, 0.21) p=0.39
Leptin	0.03 (−0.27, 0.33) p=0.84	0.11 (−0.27, 0.49) p=0.57

^*Annual change in eGFR in ml/min/1.73m²

^**Covariates in fully adjusted model include baseline age, race, gender, glucose, antihypertensive use, hypolipidemic use, HDL, D-LDL, viral load, change in viral load, change in CD4 count, duration of saquinavir exposure.