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. 2015 Feb 3;14(1):27. doi: 10.1186/s12943-015-0293-5

Table 1.

NRAS mutant cell lines and their characteristics

Cell line	NRAS mutation	Other known mutations
M202	NRAS^Q61L	EGFR amplification
M202	NRAS^Q61L	CDKN2A homozygous deletion
M207	NRAS^Q61L	MITF amplification
		EGFR L747_P753 > S
		PTEN heterozygous deletion
M243	NRAS^Q61H homozygous	PTENE156G heterozygous
M243	NRAS^Q61H homozygous	CTNNB1_D32Y
M244	NRAS^Q61K heterozygous
M245	NRAS^Q61K heterozygous	TP53R273H
M249AR4	NRAS^Q61K heterozygous	MITF amplification
	BRAF^V600E heterozygous	PTEN homozygous deletion
	BRAF^V600E heterozygous	AKT2 amplification
M296	NRAS^Q61R heterozygous
M311	NRAS^Q61L homozygous
M318	NRAS^Q61L heterozygous	PIK3CAC420R
M376	NRAS^Q61K heterozygous
M376	BRAF^V600E heterozygous
M408	NRAS^Q61K heterozygous
SBCL2	NRAS^Q61K homozygous
SKMEL173	NRAS^Q61K	CTNNB1 D32G
SKMEL173	NRAS^Q61K	CCND1 amplification
WM1366	NRAS^Q61L heterozygous