Table 1.
Patients' characteristics.
| Parameter | miR-224 low (n = 91) |
miR224 high (n = 91) |
P value |
|---|---|---|---|
| Age, years, mean ± SD | 54 ± 11.8 | 52.5 ± 9.3 | 0.366 |
| Gender (male/female) | 69/22 | 86/5 | 0.001 |
| Hepatitis B, n (%) | 74 (81.3) | 85 (93.4) | 0.015 |
| TBIL (umol/L) | 17.1 ± 8.8 | 19.1 ± 12.7 | 0.103 |
| DBIL (umol/L) | 5.7 ± 3.4 | 7.9 ± 7.2 | 0.022 |
| ALT (IU/L) | 34.6 ± 20.9 | 59.4 ± 65.9 | 0.000 |
| AST (IU/L) | 40.2 ± 23.8 | 80.5 ± 81.9 | 0.000 |
| γ-GGT (IU/L) | 126.5 ± 151.7 | 215.5 ± 223.1 | 0.000 |
| LDH (IU/L) | 198.9 ± 88.9 | 286.7 ± 177.4 | 0.000 |
| ALP (IU/L) | 122.1 ± 86.2 | 167 ± 126.7 | 0.000 |
| ALB (g/L) | 40.1 ± 4.8 | 38.2 ± 4.6 | 0.007 |
| PT (s) | 12.6 ± 0.96 | 12.9 ± 1.04 | 0.011 |
| INR | 1.07 ± 0.08 | 1.09 ± 0.09 | 0.018 |
| Child-Pugh (A/B) | 87/4 | 76/15 | 0.03 |
| BCLC (B/C) | 58/33 | 40/51 | 0.012 |
| AFP (ng/mL) | 1049 ± 1442 | 1822 ± 1702 | 0.001 |
TBIL: total bilirubin; D-TBIL: direct bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; γ-GGT: γ-glutamyl transferase; LDH: lactic dehydrogenase; ALP: alkaline phosphatase; ALB: albumin; PT: prothrombin time activity percentage; INR: international normalized ratio.