Table 2.
Univariate and multivariate Cox regression analyses of parameters associated with overall survival of all HCC patients.
| Parameters | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Gender (male versus female) | 1.659 (0.66, 4.172) | 0.282 | ||
| HBV (no versus yes) | 0.767 (0.375, 1.567) | 0.466 | ||
| Cirrhosis (no versus yes) | 1.268 (0.506, 3.181) | 0.613 | ||
| AFP (<200 versus >200 ng/mL) | 2.397 (1.339, 4.289) | 0.003 | 1.998 (1.085, 3.681) | 0.026 |
| Child-Pugh (A versus B) | 2.04 (1.041, 3.996) | 0.038 | / | / |
| BCLC (B versus C) | 4.083 (2.228, 7.482) | 0.000 | 2.865 (1.500, 5.472) | 0.001 |
| Local therapy | 0.235 (0.084, 0.654) | 0.006 | 0.170 (0.065, 0.444) | 0.000 |
| Sorafenib | 1.423 (0.791, 2.562) | 0.239 | ||
| Serum miR-224 (low versus high) | 2.188 (1.264, 3.786) | 0.005 | 2.085 (1.142, 3.807) | 0.017 |