Table 3.
Comparative serum content of oxidants, antioxidants, Cholesterol, TG, and HDL together with the activity of burst enzymes between COPD patients and controls at day 0 (i.e., on set of experiments).
| Parameters | COPD (n = 30) (mean ± SD) |
Controls (n = 20) (mean ± SD) |
t value | P value |
|---|---|---|---|---|
| Malondialdehyde (MDA) (nmoL/mL) | 3.78 ± 0.24 | 1.2 ± 0.19 | 45.623 | 0.000* |
| Lipid hydroperoxide (nmoL/mL) | 3.63 ± 0.19 | 1.25 ± 0.17 | 50.752 | 0.000* |
| Catalase (kU/L) | 31.53 ± 8.41 | 59.88 ± 7.04 | −14.156 | 0.000* |
| Superoxide dismutase (SOD) (U/mL) | 67.25 ± 6.43 | 104.33 ± 11.18 | −15.746 | 0.000* |
| Glutathione-S-transferase (GST) (U/mL) | 28.41 ± 4.02 | 39.14 ± 3.34 | −11.225 | 0.000* |
| Glutathione (GSH) (nmoL/mL) | 279.3 ± 23.26 | 414.67 ± 20.32 | −24.006 | 0.000* |
| Vitamin C (mg/dL) | 0.76 ± 0.07 | 2.15 ± 0.16 | −42.646 | 0.000* |
| Cholesterol (mg/dL) | 167.22 ± 10.33 | 188.05 ± 13.21 | −6.805 | 0.000* |
| Triglyceride (TG) (mg/dL) | 172.10 ± 14.44 | 179.67 ± 18.66 | −1.757 | 0.084 |
| High density lipoprotein (HDL) (mg/dL) | 42.21 ± 5.17 | 51.95 ± 6.36 | −6.513 | 0.000* |
*Statistically significant.