Table 5.
Serum anti-Dsg 1, serum anti-Dsg3, and salivary antidesmoglein 3 ELISA main diagnostic outcomes using the manufacturer's suggested cut-off value of 20 RU/mL.
| Serum anti-Dsg 1 ELISA | Serum anti-Dsg 3 ELISA | Salivary anti-Dsg 3 ELISA | |
|---|---|---|---|
| True positive | 62 | 83 | 63 |
| True negative | 176 | 176 | 178 |
| False positive | 4 | 4 | 2 |
| False negative | 24 | 3 | 23 |
| Sensitivity | 72.09% | 96.51% | 73.26% |
| Specificity | 97.78% | 97.78% | 98.89% |
| Positive predictive values | 0.94 | 0.95 | 0.97 |
| Negative predictive values | 0.88 | 0.98 | 0.89 |
| Test accuracy | 0.89 | 0.97 | 0.91 |
| Positive likelihood ratio | 32.44 | 43.33 | 65.93 |
| Negative likelihood ratio | 0.29 | 0.04 | 0.27 |
| Diagnostic odds ratio | 113.67 | 1217.33 | 243.78 |
| Cohen's kappa coefficient | 0.89 | 0.97 | 0.90 |