Resistance mutations are represented as occuring at >50% (“Dominant”, solid bars), >1–50% (grey hatched bars), >0.1–1% (light grey hatched bars). All mutations known to confer resistance at each position were catergorised together, irrespective of the amino acid change. For particpants who had evidence of multiple mutations at one site (eg. Both M423T andM423V), the mutation seen at higher % was reported. No mutations were found to occur in the range between 3 and 88%. Dominant resistant mutations generally occurred at > 98%.