Figure 4. A, Heart rate (HR) and B, mean arterial blood pressure (MAP) of the chemoreceptor reflex response induced by increasing doses of potassium cyanide (KCN, from 60 to 180 µg/kg) in rats that received microinjections into the posterodorsal medial amygdala of saline (0.3 µL, n=7), oxytocin (OT; 10 ng/0.3 µL and 25 pg/0.3 µL, n=6 in both groups), somatostatin (SST; 1 µM/0.3 µL, n=8 and 0.05 μM/0.3 µL, n=5), or angiotensin II (Ang II; 50 pmol/0.3 µL and 50 fmol/0.3 µL; n=7 in both groups). Data are reported as means±SD. Data were submitted to the two-way ANOVA test for repeated measures and the Newman-Keuls post hoc test. In A, for HR: *P<0.01 compared with 60 µg/kg KCN in the group microinjected with saline. **P<0.01 compared with 60 µg/kg KCN in the group microinjected with OT 10 ng. ⁺P<0.01 compared with 60 µg/kg KCN in the group microinjected with OT 25 pg. ^†P<0.01 compared with 60 µg/kg KCN in the group microinjected with SST 0.05 μM. ^‡P<0.05 compared with 60 µg/kg KCN in the group microinjected with Ang II 50 pmol. In B, for MAP: *P<0.01 compared with 60 µg/kg KCN in the group microinjected with OT 10 ng. ⁺P<0.05 compared with 140 µg/kg KCN in the group microinjected with SST 1 µM. ^†P<0.05 compared with 180 µg/kg KCN in the group microinjected with saline. ^‡P<0.05 compared with 180 µg/kg KCN in the group microinjected with OT 10 ng. Expanded and adapted from Ref. 6 with permission from Nova Science Publishers (USA).