Fig. 1.

Effect of silencing JNK pathway components on NF54 WT infections. Effect of silencing JIP1, JNK, Fos, Jun, and Puc on NF54 WT infection 7–10 d PF. Orange dots represent oocyst counts from individual mosquito midguts and medians are represented by red lines. Each phenotype was confirmed with two to three independent experiments. (Inset) A. gambiae orthologs of the Drosophila JNK signaling cascade. Geometric shapes represent genes phenotyped using RNAi. Gray color indicates that silencing had no significant effect on infection intensity.