Table 5.
Expression of genes encoding (putative) multi-drug efflux pumps (MEX pumps)
| PA30 | PA49 | ||||
|---|---|---|---|---|---|
| Gene ID/accession | Product | T | W | T | W |
| gi|15596434 | Multi-drug resistance efflux pump | n.p.a | n.p. | 8 | 6 |
| gi|491814602 | Macrolide efflux protein | n.p. | n.p. | 69 | 85 |
| gi|386336514 | RND transporter | n.p. | n.p. | 104 | 91 |
| gi|307130252 | RND efflux membrane fusion protein | n.p. | n.p. | 29 | 42 |
| PA1237 | Probable multi-drug resistance efflux pump | 9 | 6 | 10 | 0 |
| PA3719 | Anti-repressor for MexR, ArmR | 20 | 15 | 10 | 33 |
| PA4990 | SMR multi-drug efflux transporter | 103 | 79 | 21 | 15 |
| PA4374 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor | 499 | 444 | 233 | 251 |
| PA4375 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 1024 | 643 | 439 | 293 |
| PA3522 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 1090 | 102 | 381 | 82 |
| PA3523 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor | 355 | 56 | 140 | 27 |
| gi|489214414 | Outer membrane component of multi-drug efflux pump. partial | 0 | 0 | 1 | 1 |
| gi|15596434 | Multi-drug resistance efflux pump | 0 | 0 | 10 | 0 |
| PA0427 | Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor | 2722 | 2351 | 991 | 1137 |
| PA0426 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux transporter MexB | 7087 | 5994 | 2277 | 3917 |
| PA0425 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux membrane fusion protein MexA precursor | 3129 | 2318 | 1098 | 1904 |
| PA0424 | Multi-drug resistance operon repressor MexR | 1305 | 520 | 331 | 321 |
| PA1238 | Probable outer membrane component of multi-drug efflux pump | 4 | 7 | 0 | 3 |
| PA1435 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor | 44 | 40 | 16 | 23 |
| PA1436 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 158 | 181 | 70 | 61 |
| PA0158 | Resistance-Nodulation-Cell Division (RND) triclosan efflux transporter, TriC | 2826 | 2341 | 1241 | 539 |
| PA0157 | Resistance-Nodulation-Cell Division (RND) triclosan efflux membrane fusion protein, TriB | 398 | 433 | 200 | 118 |
| PA0156 | Resistance-Nodulation-Cell Division (RND) triclosan efflux membrane fusion protein, TriA | 530 | 529 | 367 | 177 |
| PA2019 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux membrane fusion protein precursor | 939 | 1323 | 79 | 70 |
| PA2018 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux transporter | 3969 | 4876 | 321 | 240 |
| PA2528 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor | 508 | 452 | 349 | 690 |
| PA2527 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 603 | 529 | 345 | 572 |
| gi|489252367 | Multi-drug transporter | 23 | 35 | 16 | 8 |
| PA2526 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 504 | 542 | 594 | 449 |
| gi|489215922 | Resistance-Nodulation-Cell Division (RND) efflux transporter. partial | 31 | 28 | n.p. | n.p. |
| PA2522 | Outer membrane protein precursor CzcC | 80 | 17 | 116 | 15 |
| PA2521 | Resistance-Nodulation-Cell Division (RND) divalent metal cation efflux membrane fusion protein CzcB precursor | 184 | 47 | 147 | 20 |
| PA2520 | Resistance-Nodulation-Cell Division (RND) divalent metal cation efflux transporter CzcA | 369 | 77 | 430 | 51 |
| PA2495 | Multi-drug efflux outer membrane protein OprN precursor | 91 | 111 | 13 | 6 |
| PA2494 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux transporter MexF | 1021 | 767 | 126 | 82 |
| PA2493 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux membrane fusion protein MexE precursor | 110 | 106 | 35 | 61 |
| PA1541 | Probable drug efflux transporter | 38 | 104 | 148 | 1088 |
| PA5160 | Drug efflux transporter | 225 | 208 | 191 | 128 |
| PA4206 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor | 49 | 54 | 11 | 80 |
| PA4207 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 175 | 146 | 58 | 99 |
| PA4597 | Multi-drug efflux outer membrane protein OprJ precursor | 42 | 142 | 28 | 197 |
| PA4598 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux transporter MexD | 153 | 297 | 83 | 964 |
| PA4599 | Resistance-Nodulation-Cell Division (RND) multi-drug efflux membrane fusion protein MexC precursor | 16 | 66 | 31 | 583 |
| PA3676 | Probable Resistance-Nodulation-Cell Division (RND) efflux transporter | 385 | 503 | 141 | 233 |
| PA3677 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor | 24 | 72 | 23 | 70 |
a
n.p. – gene sequence is not present in this strain.
Identifiers state PAO1 gene IDs or RefSeq accession where applicable. Transcriptional activity in tap water (T) and waste water (W) was normalized for the two strains independently and is shown as normalized pseudocounts.