. 2015 Jan 19;50(1):59–71. doi: 10.1310/hjp5001-059

Table 1. US Food and Drug Administration–approved indications for nonbenzodiazepine hypnotics ^1–7.

Agent	Class	Indications
		Treatment of insomnia characterized by difficulty with sleep onset	Treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance	Treatment of insomnia characterized by difficulties with sleep maintenance

Suvorexant	Orexin receptor antagonist		X

Doxepin	Tricyclic antidepressant			X

Eszopiclone	Benzodiazepine receptor agonist		X

Ramelteon	Melatonin receptor agonist	X

Zaleplon	Benzodiazepine receptor agonist	X

Zolpidem extended release	Benzodiazepine receptor agonist		X

Zolpidem immediate release	Benzodiazepine receptor agonist	X

Table 1. US Food and Drug Administration–approved indications for nonbenzodiazepine hypnotics 1–7.