Table 3.

Spearman correlation of methylation levels of the HES4 promoter with HD sample characteristics

	Hyper-methylation	Intermediate methylation	Un-methylated
Striatal involvement	−0.22	0.56	−0.36
P-value	0.32	0.006	0.10
n	22	22	22
Cortical involvement	−0.33	0.09	0.06
P-value	0.13	0.69	0.79
n	22	22	22
Onset age	−0.037	−0.48	0.39
P-value	0.87	0.02	0.0661
n	23	23	23
HD CAG repeat	−0.15	0.50	−0.35
P-value	0.47	0.01	0.08
n	25	25	25