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. 2015 Jan 28;71(Pt 2):145–148. doi: 10.1107/S2053230X14027599

Figure 2.

Figure 2

Comparison of apo and HA-bound structures of the CH65–CH67 antibody lineage. (a) The heavy variable (VH) and light variable (VL) Ig domains are depicted and the HCDR3 loops of the UCA (PDB entry 4hk0; Schmidt et al., 2013 ▶), I-2 (PDB entry 4hk3; Schmidt et al., 2013 ▶), apo CH65 (PDB entry 4wuk) and HA-bound CH65 (PDB entry 3sm5) are shown as thick tubes. Spheres indicate amino-acid positions that differ between the UCA and the CH65 and CH67 antibodies. (b) Enlarged view of the HCDR3 loops.