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. 2015 Feb 9;9:21. doi: 10.3389/fncel.2015.00021

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Copyright © 2015 Ramos-Chávez, Rendón-López, Zepeda, Silva-Adaya, Del Razo and Gonsebatt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of As exposure on the spatial working memory in the recognition place task in male and female mice on PND 90. Discrimination index (DI) = (novel place exploration time/total exploration time). (A) male and female DI of location in the recognition phase and (B) during test phase in controls, animals exposed during gestation and lactation (iAs-PND 15) and animals exposed during gestation, lactation and until PND 90 (iAs-PND 90). Each bar represents the mean ± SE (n = 8). Data were analyzed using an ANOVA. (*) Significantly different from controls after Dunnett’s post hoc test, P < 0.05. # P = 0.0625.