Table S1.
Baseline demographics in subjects with a high baseline aortic pulse wave velocity
| Mean (SD) Unless otherwise specified | Active treatment (simvastatin) group | Placebo |
|---|---|---|
| Total number of patients, n | 12 | 13 |
| Age (years), median (range) | 70 (54–77) | 64 (52–75) |
| Male sex, n (%) | 9 (75) | 10 (77) |
| Smoking status (current:ex) | 4:8 | 5:8 |
| Pack years, median (IQR) | 41.5 (33–50) | 53 (37–68) |
| Aortic PWV (m/sec) | 13.2 (2.9) | 12.0 (2.1) |
| Peripheral systolic BP (mmHg) | 156 (27) | 159 (31) |
| Peripheral diastolic BP (mmHg) | 94 (14) | 90 (18) |
| FEV1 (L) | 1.4 (0.6) | 1.6 (0.7) |
| FEV1 % predicted | 51 (13) | 55 (17) |
| FEV1/FVC | 41 (8) | 48 (10) |
| Total cholesterol (mmol/L) | 5.3 (0.8) | 5.3 (0.8) |
| HDL cholesterol (mmol/L) | 1.7 (0.4) | 1.7 (0.5) |
| LDL cholesterol (mmol/L) | 3.0 (0.6) | 2.8 (0.7) |
Abbreviations: PWV, pulse wave velocity; BP, blood pressure; FEV1, forced expired volume in one second; FVC, forced vital capacity; HDL, high-density lipoprotein; IQR, interquartile range; L, liter; LDL, low-density lipoprotein; SD, standard deviation.