Table S3.
Patient-reported side effects and blood tests for safety
| Active treatment (simvastatin) group | Placebo group | |
|---|---|---|
| Adverse events/Musculoskeletal | ||
| Muscle cramps | 2 | 0 |
| Muscle aches | 5 | 2 |
| Joint aches | 0 | 2 |
| Respiratory | 4 | 3 |
| Gastrointestinal | 1 | 1 |
| Severe adverse events | ||
| Hospital admissions | 0 | 0 |
| Death | 0 | 0 |
| Change in LFTs | ||
| Clinically relevant increase in ALT | 0 | 0 |
| Clinically relevant increase in gamma GT | 1 | 1 |
| Clinically relevant increased CPK | 0 | 1 |
Abbreviations: ALT, alanine aminotransferase; gamma GT, gamma-glutamyl transferase; CPK, creatine phosphokinase; LFTs, lung function tests.