Figure 5.

In vitro selective inhibition of BCSC-DCs and MSC-DCs.

Notes: BCSC-DCs and MSC-DCs incubated with CTLs at different ratios of DCs:CTLs suppressed BCSC proliferation and were measured by impedance using xCELLigence (A). Before adding CTLs, the cell proliferation rate in all groups was non-different from the control (B, D). After adding CTLs, MSC-DCs reduced proliferation rate compared with the control, while BCSC-DCs significantly inhibited BCSC proliferation at a DC:CTL ratio of 1:40 (C, E).

Abbreviations: BCSC, breast cancer stem cells; CTL, cytotoxic T lymphocyte; DC, dendritic cells; MSC, mesenchymal stem cells.