The HIV coreceptor CCR5 is differentially expressed on CCR4+CCR6+, CCR4+CCR6−, CXCR3+CCR6+, and CXCR3+CCR6− T cells. A– C, The expression of the HIV coreceptors CCR5 and CXCR4 was analyzed in CCR4+CCR6+, CCR4+CCR6−, CXCR3+CCR6+, and CXCR3+CCR6− T cells gated as in Fig. 1A and 1B. A, Shown are histograms of CCR5 and CXCR4 expression in T cell subsets from one representative donor; B, statistical analysis of CCR5 expression (percentage and mean fluorescence intensity) in T cell subsets from n = 13 different donors; and C, statistical analysis of CXCR4 expression (percentage and mean fluorescence intensity) in T cells from n = 7 different donors. Wilcoxon signed-rank test p values are indicated in the figure. Horizontal lines indicate median values.