. Author manuscript; available in PMC: 2015 Feb 9.

Published in final edited form as: Br J Dermatol. 2013 Jul;169(0 2):1–8. doi: 10.1111/bjd.12208

Table 2.

Sites of superoxide and hydrogen peroxide production associated with oxidative phosphorylation in mitochondria

Site	References
Citric acid cycle
Pyruvate dehydrogenase	55
2-oxoglutarate dehydrogenase	55–57
Dihydrolipoamide dehydrogenase	58
Ubiquinone reduction pathways
Complex II flavin (site IIF)	59
Electron transferring flavoprotein/ETF:Q oxidoreductase	50
Glycerol 3-phosphate dehydrogenase	47,60
Dihydroorotate dehydrogenase	47
Electron transport chain
Complex I flavin (site IF)	61
Complex I ubiquinone (site IQ)	61–63
Complex III outer ubiquinone binding site (site IIIQo)	40,64