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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Bioanalysis. 2014 Dec;6(23):3081–3089. doi: 10.4155/bio.14.254

Table 3.

Precision of peak areas and peak area ratio in set 1 and 2 (n = 6).

Conc
(ng/ml)
PQ peak area CV (%)
IS peak area CV (%)
Peak area ratio CV (%)
Set 1 Set 2 Set 2–Set 1 Set 1 Set 2 Set 2–Set 1 Set 1 Set 2 Set 2–Set 1
Low (3.0) 5.2 1.6 −3.6 7.5 4.5 −3.0 4.3 3.9 −0.4

Medium (20) 5.3 2.5 −2.8 5.9 2.9 −3.0 3.2 4.1 0.9

High (200) 4.8 3.5 −1.3 5.5 2.2 −3.4 1.1 4.1 3.1

Set 1 samples prepared in 5% trichloroacetic acid in MeOH-water(1:1, v/v), set 2 samples prepared in six different lots of plasma.

Conc: Concentration; CV: Coefficient of variation; IS: Internal standard; PQ: Piperaquine.